for people ages 18 years and up (full criteria)
Healthy Volunteers
healthy people welcome
at San Francisco, California
study started
estimated completion
Principal Investigator
by Andreea L. Seritan, MD
Photo of Andreea L. Seritan
Andreea L. Seritan



This study aims to explore the feasibility and effectiveness of mindfulness-based cognitive therapy (MBCT) in reducing anxiety and/or depressive symptoms in people with Parkinson's disease (PD) and caregivers of people with PD.

Official Title

Mindfulness-based Cognitive Therapy for People With Parkinson's Disease and Caregivers


An adapted MBCT intervention will be offered to people with Parkinson's disease (PD) and mild-to-moderate depression and/or anxiety, as well as caregivers of people with PD. Several 8-week long MBCT groups will be held between September 2020 and May 2021, based on the adapted protocol. The MBCT intervention will consist of 90-minute weekly groups focused on teaching mindfulness techniques and ways to recognize cognitive patterns that can increase anxiety and/or depression. Participants will be recruited from the community, according to the eligibility criteria detailed below. For all participants, the pre- and post-MBCT anxiety and/or depressive symptom severity and mindfulness levels (as measured with standardized, validated scales) will be compared, using a paired t-test. For caregivers, pre- and post-MBCT caregiver burden scores will be compared as well.


Parkinson Disease Anxiety Depression Parkinson's disease Mindfulness-based intervention Mindfulness-based cognitive therapy (MBCT)


You can join if…

Open to people ages 18 years and up

  • Having a diagnosis of Parkinson's disease (PD) or parkinsonism, established by a neurologist, or being a caregiver of a person with PD or parkinsonism
  • Being able and willing to attend 8 weekly 90-minute online group sessions (5-6:30 pm PST)
  • Mild-to-moderate anxiety: GAD-7 score ≤ 16
  • Mild-to-moderate depression: PHQ-9 score ≤ 18

You CAN'T join if...

  • Severe anxiety: GAD-7 score > 16
  • Moderately severe-to-severe depression: PHQ-9 score > 18
  • Cognitive impairment: Montreal Cognitive Assessment (MoCA) score < 24
  • Heavy alcohol or drug use
  • Severe psychosis
  • Active suicidal or homicidal ideation
  • For people with PD: severe motor fluctuations (less than 2 hours "on" time per day)
  • Pattern of engagement with health care that indicates low likelihood of completing an 8-week intervention.


  • University of California, San Francisco
    San Francisco California 94143 United States

Lead Scientist at UCSF

  • Andreea L. Seritan, MD
    Dr. Seritan is a geriatric psychiatrist whose clinical work focuses on understanding and managing the psychiatric manifestations of neurodegenerative diseases. Dr. Seritan developed and leads the Clinical Neurosciences Area of Distinction for psychiatry residents, is a member of the Haile T.


in progress, not accepting new patients
Start Date
Completion Date
University of California, San Francisco
Study Type
Last Updated