Summary

Eligibility
for people ages 18 years and up (full criteria)
Location
at San Francisco, California
Dates
study started
completion around
Principal Investigator
by Simon J Little, MBBS, PhD
Headshot of Simon J Little
Simon J Little

Description

Summary

The study's aim is to better understand motivation and value-based decision making in Parkinson's patients through neurophysiology using Medtronic's Percept PC DBS device.

Details

The investigators will ask patients to complete reward-based decision making tasks in clinic and at home in the presence and absence of Percept PC deep brain stimulation and medication. The Percept PC device has the ability to stream data during paradigms and chronically at home. Patients at home will also be fitted with a wearable device which records motion, sleep, heart rate variability, and self-reported metrics. The investigators will use spectral techniques and statistical analysis to identify the relationship between brain signals and motivation.

Keywords

Parkinson Disease, Deep Brain Stimulation, Motivation, Parkinson's, Medtronic, Percept PC, DBS, Parkinson's Disease, PD, Reward-based decision making, Task, Percept, Stimulation on, Stimulation off, Decision Making Task, Stimulation

Eligibility

You can join if…

Open to people ages 18 years and up

  • Has Parkinson's Disease
  • Has Medtronic Percept PC DBS device implanted in either GPI or STN

You CAN'T join if...

  • Severe cognitive impairments

Location

  • UCSF accepting new patients
    San Francisco California 94158 United States

Lead Scientist at UCSF

  • Simon J Little, MBBS, PhD
    Dr. Simon Little is a neurologist who specializes in caring for patients with movement disorders, including Parkinson's disease, tremor and dystonia (involuntary muscle contractions that can cause repetitive movements and abnormal posture).

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, San Francisco
ID
NCT05065151
Study Type
Interventional
Participants
Expecting 20 study participants
Last Updated