for people ages up to 25 years (full criteria)
at San Francisco, California and other locations
study started
completion around
Principal Investigator
by Phil Rosenthal, MD
Headshot of Phil Rosenthal
Phil Rosenthal



This study involves the one-time collection of whole blood or saliva samples for the extraction and storage of DNA for use in ongoing and future ChiLDReN studies.


The purpose of this study is to establish a mechanism to collect a genetic biosample from the participants and their biological parents previously enrolled into clinical research under ChiLDReN-supported protocols (PROBE, BASIC, LOGIC, and MITOHEP). The samples will be linked to the data previously collected on the participant. Samples will be stored in the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) specimen repository and will be used in ongoing and future Network and Ancillary Studies of ChiLDReN to further address the pathophysiology and outcomes of these liver diseases.


Liver Diseases


You can join if…

Open to people ages up to 25 years

  • For Child Participants
    1. Previous enrollment in PROBE, BASIC, LOGIC, or MITOHEP
    2. Exited from one of the aforementioned studies.
    3. Consent for DNA sample collection obtained during enrollment during enrollment to one of the aforementioned studies but sample not previously collected.
    4. Still followed at the clinical site.
  • For Biological Parent Participants
    1. Biological parents of previously consented child participant without collection of a parental DNA biospecimen.
    2. Child still followed at the clinical site.

You CAN'T join if...

  • For Child Participants
    1. Participant is deceased
    2. Participant exited from prior study due to violating eligibility criteria
    3. Participant cannot be contacted
  • For Biological Parent Participants
    1. Non-biological parent
    2. Child DNA was not previously collected and will not be collected in this study


  • UCSF Benioff Children's Hospital not yet accepting patients
    San Francisco California 94143 United States
  • Children's Hospital of Los Angeles accepting new patients
    Los Angeles California 90027 United States
  • University of Utah accepting new patients
    Salt Lake City Utah 84113 United States

Lead Scientist at UCSF

  • Phil Rosenthal, MD
    We have three main areas of interest, all involving malaria, one of the most important infections of humans. First, we study the basic biology of malaria parasites, including the biochemical properties and biological roles of parasite proteases and mechanisms of action of novel antimalarial agents.


accepting new patients at some sites,
but this study is not currently recruiting here
Start Date
Completion Date
Arbor Research Collaborative for Health
Study Type
Expecting 2230 study participants
Last Updated