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for people ages 18 years and up (full criteria)
at San Francisco, California
study started
estimated completion:



Major depressive disorder affects over 120 million people worldwide. Only 50% of Americans with depression receive adequate treatment, and one-third of those receiving treatment do not benefit. In this pilot project investigators will bring together two approaches that have the promise to reach large numbers of depression sufferers: a skills-based intervention for increasing positive affect and experiences in depressed individuals, delivered in an inexpensive self-paced mobile format. The study will make use of smartphone technology to improve conventional outcome measurement via in-the-moment emotion sampling and mobile assessment of heart rate variability, a predictor of cardiac health that may mediate some of the health effects of depression. The aims are: 1) Retool the existing web-based positive emotion intervention for use on smartphones, with innovative exercises that help participants bring the skills they are learning into real- life situations; 2) Measure heart rate variability and emotions using existing smartphone software; and 3) Perform a randomized pilot trial of the mobile intervention on individuals with clinical depression recruited online.

Official Title

Online Positive Emotion Skills Intervention for Symptoms of Depression - Pilot Feasibility Trial


Depression Psychological Stress Affect Depressive Disorder Stress, Psychological


You can join if…

Open to people ages 18 years and up

  • Daily internet access
  • Cell phone ownership
  • Score of 10 or greater on the PHQ-8 depression scale

You CAN'T join if...


  • University of California, San Francisco - Osher Center for Integrative Medicine
    San Francisco, California, 94143-1726, United States


in progress, not accepting new patients
Start Date
Completion Date
University of California, San Francisco
Lead Scientists
Judith T Moskowitz
Michael A Cohn
Study Type
Last Updated
May 2016