Summary

Eligibility
for people ages 18-85 (full criteria)
Healthy Volunteers
healthy people welcome
Location
at San Francisco, California and other locations
Dates
study started
completion around
Principal Investigator
by Adam Boxer, MD, PhDHowie Rosen, MD
Headshot of Adam Boxer
Adam Boxer
Headshot of Howie Rosen
Howie Rosen

Description

Summary

This is a biomarker study designed to collect and analyze blood specimens from individuals carrying known familial frontotemporal lobar degeneration (f-FTLD) mutations compared to a control group of individuals without known f-FTLD mutations. The NSP is an ancillary study to the ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration" (ALLFTD) study, NCT04363684. More information can be found at https://www.allftd.org/.

Official Title

Remote Blood Biomarker Monitoring in Frontotemporal Lobar Degeneration: Neurofilament Surveillance Project (NSP)

Details

Keywords

Frontotemporal Dementia, Frontotemporal Lobar Degeneration, FTD-GRN, FTD, FTLD, C9orf72, GRN, MAPT, Primary Progressive Aphasia, Pick Disease of the Brain, f-FTLD mutation carriers

Eligibility

Locations

  • UCSF
    San Francisco California 94158 United States
  • Mayo Clinic
    Rochester Minnesota 55905 United States

Lead Scientists at UCSF

  • Adam Boxer, MD, PhD
    Adam L. Boxer, MD, PhD is the Endowed Professor in Memory and Aging in the Department of Neurology, Weill Institute of Neuroscience, University of California, San Francisco (UCSF). He received his MD and PhD from the New York University Medical Center Medical Scientist Training Program, completed a Neurology Residency at Stanford and a Neurobehavior Fellowship at UCSF.
  • Howie Rosen, MD
    Professor, Neurology, School of Medicine. Authored (or co-authored) 371 research publications

Details

Status
in progress, not accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
The Bluefield Project to Cure Frontotemporal Dementia
Links
ALLFTD is the parent study of the NSP.
ID
NCT04516499
Study Type
Observational
Participants
About 342 people participating
Last Updated