This study is in progress, not accepting new patients

PrEP Affect Regulation Treatment Innovation

a study on Treatment Adherence HIV/AIDS Stimulant Use PrEP

Summary

Eligibility
for males ages 18 years and up (full criteria)
Healthy Volunteers
healthy people welcome
Location
at San Francisco, California and other locations
Dates
study started
completion around

Description

Summary

This multi-site randomized controlled trial enrolling sexual minority men who use stimulants and are currently taking pre-exposure prophylaxis (PrEP). This randomized controlled trial will test the efficacy of a PrEP Affect Regulation Treatment Innovation (PARTI) condition comprised of a 5-session positive affect intervention delivered during smartphone-based Contingency Management (CM) for directly observed PrEP doses (PARTI+CM) compared to an attention-control condition delivered during CM. The primary outcome is HIV acquisition risk measured using a combination of tenofovir-diphosphate levels in dried blood spots that are indicative of sub-optimal adherence to PrEP and recent condomless anal sex.

Official Title

Optimizing PrEP Adherence in Sexual Minority Men Who Use Stimulants

Keywords

Medication Adherence, HIV Prevention, Stimulant Use, Sexual Minority Men, HIV, PrEP Adherence, Contingency Management, PARTI, Contingency Management for PrEP Adherence, PARTI and CM (Contingency Management)

Eligibility

Locations

  • UCSF
    San Francisco California 94143 United States
  • University of Miami Miller School of Medicine
    Miami Florida 33136 United States

Details

Status
in progress, not accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
Florida International University
ID
NCT04899024
Study Type
Interventional
Participants
About 239 people participating
Last Updated