Summary

Eligibility
for people ages 18 years and up (full criteria)
Location
at San Francisco, California and other locations
Dates
study started
estimated completion
Principal Investigator
by Robert Rodriguez, MD

Description

Summary

The goal of this research is to increase COVID-19 and influenza vaccine acceptance and uptake in vulnerable populations whose primary (and often only) health care access occurs in emergency departments (ED Usual Source of Care Patients). Toward this goal, the investigators will conduct one on one interviews and focus groups with ED Usual Source of Care Patients and community partners and produce trusted messaging informational platforms (PROmotion of COvid-19 VA(X)ccination in the Emergency Department - PROCOVAXED) that will address barriers to COVID-19 and influenza vaccination, especially vaccine hesitancy. The investigators will then conduct a cluster-randomized, controlled trial of PROCOVAXED platforms in six EDs to determine whether their implementation is associated with greater COVID-19 and influenza vaccine acceptance and uptake in ED Usual Source of Care Patients.

Details

The investigator's preliminary work research at 15 ED sites across the US indicates that ED Usual Source of Care patients have particular health care access barriers, needs, and perceptions about vaccines (vaccine hesitancy) that require specific review beyond traditional (non-ED user) community engagement techniques. To gain insight about messaging that effectively addresses these barriers, needs, and perceptions, the investigators will conduct one on one interviews and focus group meetings with ED Usual Source of Care Patients and community partners. At five safety net EDs (Zuckerberg San Francisco General, Thomas Jefferson University Hospital [Philadelphia], Methodist Hospital [Philadelphia], Harborview Medical Center [Seattle], and Duke University Medical Center [Durham, NC], the investigators will conduct a cluster-randomized, controlled trial of implementation of PROCOVAXED platforms, with COVID-19 and influenza vaccine acceptance rates on post-intervention ED surveys as the primary outcomes. Hypothesis: Implementation of PROCOVAXED platforms in EDs will be associated with increased acceptance of COVID-19 and influenza vaccines in ED patients. One month after subjects' index ED visit enrollment in our PROCOVAXED implementation trial, the investigators will conduct electronic health record review and phone follow-up surveys to determine ED patient uptake (receipt) of COVID-19 and influenza vaccines. Hypothesis: Implementation of PROCOVAXED platforms in EDs will be associated with greater COVID-19 and influenza vaccine uptake in ED patients. The investigators will conduct a cluster-randomized, controlled trial (RCT) of implementation of our PROCOVAXED platforms in 5 high-volume, safety net hospital EDs, testing two hypotheses that implementation of PROCOVAXED platforms will be associated with increased acceptance and uptake of COVID-19 and influenza vaccines in ED Usual Source of Care Patients.

Keywords

Covid-19 Vaccine Vaccine Hesitancy COVID-19 Emergencies Covid-19 vaccine education materials

Eligibility

You can join if…

Open to people ages 18 years and up

  • Adults (>18 years of age) patients who are receiving care at participating Emergency Departments and have not yet received a COVID-19 vaccine

You CAN'T join if...

  • major trauma patients
  • patients transferred from another hospital, chronic care facility, nursing home or hospice,
  • patients unable to participate in an interview because of intoxication, altered mental status or critical illness
  • incarcerated patients
  • patients on psychiatric holds
  • patients who have received a COVID-19 vaccine
  • under suspicion for acute COVID-19 illness

Locations

  • San Francisco General Hospital Emergency Department accepting new patients
    San Francisco California 94110 United States
  • University of California, San Francisco - Parnassus accepting new patients
    San Francisco California 94143 United States

Lead Scientist at UCSF

  • Robert Rodriguez, MD
    Professor, Emergency Medicine, School of Medicine. Authored (or co-authored) 103 research publications. Research interests: Implementation Science · limited English proficiency · Socioeconomically marginalized groups · Migrants/refugees · trauma patients · injection drug users · Hospital · Department of public health · Decision aids · Education · trauma · immigrants · defensive medicine

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, San Francisco
ID
NCT05142332
Study Type
Interventional
Participants
Expecting 1290 study participants
Last Updated